Analytical Chemistry Services

Employing state-of-the-art instrumentation in HPLC, GC, GC/MS and LC/MS/MS, Synomics Pharma can develop analytical chemistry methods from first principles to validation and can verify or improve existing methods for the analysis of a wide range of active compounds. Customized analytical chemistry testing and structure elucidation are also offered. All services can be provided to meet either GLP or cGMP guidelines (or non-GLP as requested):

Analytical Chemistry Services

• Method development
• Method validation
• Method verification/transfer
• Sample analysis
• Lot and batch release testing
• Structure elucidation
• Detection and identification of impurities
• Residual solvent analysis
• Dissolution testing
• Product composition
• Content – uniformity/impurities
• Customized LC/MS/MS method development
• Raw material testing
• Placebo and excipient testing
• Physical-chemical properties
• Customized analytical testing

Expertise

Proteins and Peptides

• Client specific compounds(Oncology, Neurological, and Antibody conjugates)

Glycosylated Peptides/proteins (HPLC Corona Aerosol Detector & LC/MS/MS) and
Small Molecules

• Oncology
• Hormones/prostaglandins
• Cyclodextrins
• Vitamin D derivatives
• Anti-inflammatory

Stages of Development

• Discovery (Non-GLP)
• Pre-clinical (GLP)
• Clinical (GLP/GMP)
• Commercial (cGMP)